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For full prescribing information, please refer to the Kineret® Summary of Product Characteristics.

	The recommended dose of Kineret® (anakinra) is 100 mg administered once daily via subcutaneous injection.1
	The dose should be administered at approximately the same time of day every day.1
	No dose titration is required with Kineret® (anakinra).
	Kineret® (anakinra) can easily be self-administered.

Dispensing and Storage
Kineret® (anakinra) is formulated as a sterile, colourless, preservative-free liquid with a pH of 6.5 for daily subcutaneous injection.¹

For patient convenience, Kineret® (anakinra) is supplied in single-use, 1-mL pre-filled glass syringes with 27-gauge needles. Each pre-filled glass syringe contains 0.67 mL (100 mg) of Kineret® (anakinra). Kineret® (anakinra) is dispensed in packs containing one and seven syringes. It is also available in a 4 x 7 syringe dispensing pack (28 syringes).

Additional storage information:¹

	Kineret® (anakinra) should not be used beyond the expiry date shown on the packaging.
	Kineret® (anakinra) should be stored in a refrigerator at 2° to 8°C. Do not freeze or shake.
	Protect from light.
	Before administration, inspect the solution for visible particles. Only particle-free clear, colourless-to-white solutions should be injected.

Formulation

Each pre-filled syringe (0.67 mL) contains 100 mg of anakinra in a sterile, preservative-free solution (pH 6.5) consisting of:¹

	1.29 mg sodium citrate
	5.48 mg sodium chloride
	0.12 mg disodium EDTA
	0.70 mg polysorbate 80
	water for injection.

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Kineret® Summary of Product Characteristics

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References

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1.	Kineret® (anakinra) [summary of product characteristics]. Europe B.V. 2003